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产品目录

PDGFR alpha/PDGFRA抗体图片
产品货号:
Z35992
中文名称:
PDGFR alpha/PDGFRA抗体
英文名称:
Anti-PDGFR alpha/PDGFRA Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称Anti-PDGFR alpha/PDGFRA Antibody
指标别名platelet derived growth factor receptor alpha;CD140A;PDGFR-2;PDGFR2;PDGFRA
克隆性Monoclonal
检验物种human,mouse,rat
应用范围WB
基因名称PDGFRA
抗体来源Rabbit
抗体类型IgG
免疫原A synthesized peptide derived from human PDGFR alpha
实际分子量180KD
成分500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol.
纯化方式Affinity-chromatography
浓度500μg/mL
产品形态溶液
保存条件12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing.
背景资料PDGFRA (Platelet-derived growth factor receptor,alpha),also called PDGFR2,encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family.The PDGFA gene is mapped on 4q12.The PDGFRA-FIP1L1 gene is a constitutively activated tyrosine kinase that transforms hematopoietic cells and is a therapeutic target of imatinib.And the PDGFRA gene contains 23 exons spanning about 65kb.Using the human PDGFRA promoter linked to a luciferase reporter,Joosten et al.showed that PAX1 acts as a transcriptional activator of the PDGFRA gene in differentiated human embryonal carcinoma cells.PDGFRA is responsible for mediating cellular contraction of multiple growth factors:TGFB1 and members of the PDGF family.Lei et al.noted that in the rabbit model of the disease,PDGFRA is dramatically more capable of promoting PVR than is the closely related PDGFRB.PDGFRA is a critical receptor required for human CMV infection,and thus a target for novel antiviral therapies.
Uniprot IDP16234
基因名全称Platelet-derived growth factor receptor alpha
推荐稀释比
Western blot (WB) 1:500~2000

相关搜索:PDGFR alpha/PDGFRA抗体PDGFR alpha抗体PDGFRA单抗Anti-PDGFR alpha/PDGFRA Antibody
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